How does Lactobacillus reuteri DSM17938 increase testicle size?

What is Lactobacillus reuteri DSM17938?

Definition
Lactobacillus reuteri (L. reuteri) is a well-studied probiotic bacterium that can colonize a large number of mammals. In humans, it is found in the gastrointestinal tract, urinary tract, skin, and breast milk.

Lactobacillus reuteri DSM 17938 is the daughter strain of L. reuteri ATCC 55730. The latter was originally isolated from the breast milk of a Peruvian mother, and it may be present in normal humans on the mucosa of the gastric corpus and antrum, duodenum, and ileum.

History
Lactobacillus reuteri is named after Gerhard Reuter, a German microbiologist who spent most of his career understanding the human intestinal microbiota with a focus on lactobacilli and bifidobacteria.

Benefits
L. reuteri has been demonstrated beneficial in the prevention and/or treatment of many conditions including diarrhea, functional abdominal pain, caries, atopic dermatitis, allergy, feeding intolerance, and regurgitation. Infant colic, for example, has been the major therapeutic target of L. reuteri.

Different strains of Lactobacillus reuteri
One of the most studied probiotics in the world. BioGaia’s probiotic products with Lactobacillus reuteri are among the most scientifically well-documented probiotics in the world.

Available probiotic strains with L. reuteri are as follows:
L. reuteri Protectis (L. reuteri DSM 17938) – for gut comfort
L. reuteri Prodentis (L. reuteri DSM 17938 and L. reuteri ATCC PTA 5289) – for gums and teeth
L. reuteri Gastrus (L. reuteri DSM 17938 and L. reuteri ATCC PTA 6475) – for GI tract
L. reuteri Osfortis (L. reuteri ATCC PTA 6475) – for bone health
L. reuteri Colus (L. reuteri DSM 4659) – under development for colon health

What foods contain Lactobacillus reuteri?
Lactobacillus reuteri is a probiotic culture and a member of the NSLAB population in several cheese varieties (e.g., Cheddar, Grana Padano, Gruyère, Idiazabal, Parmigiano Reggiano, Roncal, and Toma).

Does Lactobacillus reuteri increase testicle size?
The decline of circulating testosterone levels in aging men is associated with adverse health effects. During studies of probiotic bacteria and obesity, we discovered that male mice routinely consuming purified lactic acid bacteria originally isolated from human milk had larger testicles and increased serum testosterone levels compared to their age-matched controls. Further investigation showed that mice consuming Lactobacillus reuteri in their drinking water had significantly increased seminiferous tubule, and increased spermatogenesis and Leydig cell numbers per testis. This showed that criteria of gonadal aging were reduced after routinely consuming a purified microbe such as L. reuteri.

Can Lactobacillus reuteri cause diarrhea?
Lactobacillus reuteri is of human origin and is a natural colonizer of the gastrointestinal tract. In this trial, exogenously administered L. reuteri was studied as a therapeutic agent in acute diarrhea. Results show, only 26% of patients receiving L. reuteri had watery diarrhea after the second day of treatment, as compared to the 81% of those receiving placebo. Therefore they conclude that Lactobacillus reuteri is effective as a therapeutic agent in acute rotavirus diarrhea in children.

Benefits of Lactobacillus reuteri DSM17938 probiotics?
Uses
Intestinal health
One of the better-documented effects of L. reuteri is in the treatment of diarrheal diseases in children, where it significantly decreases symptom duration.
L. reuteri may be effective in treating necrotizing enterocolitis in preterm infants.
L. reuteri is an effective treatment against infant colic.

Oral health
L. reuteri may be capable of promoting dental health, as it has been proven to kill Streptococcus mutans, a bacterium responsible for tooth decay.
Gingivitis may be ameliorated by the consumption of L. reuteri.

General health
By protecting against many common infections, L. reuteri promotes overall wellness in both children and adults. Double-blind, randomized studies in child care centers have found L. reuteri-fed infants fall sick less often, require fewer doctor visits, and are absent fewer days from the center.

Safety
The manipulation of the gut microbiota is complex and may cause bacteria-host interactions. Although probiotics, in general, are considered safe, concerns exist about their use in certain cases.

Who should not take Lactobacillus reuteri DSM17938 probiotics?
Some people, such as those with compromised immune systems, short bowel syndrome, central venous catheters, heart valve disease, and premature infants, may be at higher risk for adverse events. Rarely, consumption of probiotics may cause bacteremia, fungemia, and sepsis, potentially fatal infections, in children with lowered immune systems or who are already critically ill.

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